About megatomi.com
About megatomi.com
Blog Article
Our new Apparent+ tissue clearing strategy is the only real technique that delipidates samples with no transform in morphology and with minimum influence on structural integrity.
Megatome can be a vibrating microtome made to part a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables high-throughput tissue sectioning with uniform area profile, as well as minimum tissue injury and data reduction.
Antibodies may possibly acquire weeks to diffuse via only a few millimeters of tissue, using a steep labeling gradient from floor to Main.
Working the CLI directly from a Gradle task is not at the moment supported. A distribution has to be designed by using gradlew :j2d-cli:distZip to produce a zip file containing every little thing required to run.
SE takes advantage of a rotational electric field to disperse extremely electromobile molecules (like antibodies or surfactant micelles) during a porous sample with no detrimental electrically billed constructions throughout the tissue. This enables 2-4 day clearing of intact organs,
Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely clear. This permits gentle penetration to the sample and assures the acquisition of megatomi.com high-resolution, in-concentrate impression knowledge.
Megatome is a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue problems and data decline.
eFLASH is actually a quick tissue labeling technique that allows for uniform whole-organ staining in twenty rounds of labeling.
Absolutely delipidate complete mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single 7 days with our passive clearing kit.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, shielding specimens for numerous rounds of processing.
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Our novel SHIELD tissue preservation method types intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.